Hudson Meek was born in Alabama and lived in the Birmingham suburb of Vestavia Hills. Along with his brother Tucker, he began acting at an early age. In 2014, he briefly appeared in the film The Santa Con, broadcast on the Lifetime television channel in 2014. He later appeared in episodes of the MacGyver reboot, and as a young protagonist in Baby Driver in 2017. He also acted in the television series Found in 2023, and in the feature film The School Duel in 2024. He was cast as Chris Piper in the film 90 Minutes in Heaven. In September 2024, Meek had attended the Deauville American Film Festival in France, where The School Duel, a dystopian thriller film in which he participated, premiered. On December 19, 2024, Meek fell from a vehicle traveling in Vestavia Hills. He was taken to University Hospital in Birmingham, where he died from his injuries on December 21, 2024, aged 16.